Endocrine Abstracts

Introduction: Pregnancy induces significant hormonal alterations, potentially affecting thyroid hormones. Our study aimed to assess the prevalence of thyroid dysfunction in pregnant women diagnosed with gestational diabetes Mellitus (GDM).Methods: A descriptive study was conducted, including 197 pregnant women diagnosed with GDM, under the care and monitoring at the Diabetology, Endocrinology department in Farhat Hached university Hospital, Sousse Tunisi...

Introduction: COVID-19 is a viral infection that can affect various endocrine tissues, including the thyroid. In some patients, symptoms may persist after the infection, defined as Long COVID. Given the similarity of some of these symptoms to those encountered in thyroid disorders, we have decided to assess thyroid function in patients previously infected with SARS-CoV-2.Patients & Methods: This was a prospective study conducted from January to Decem...

Introduction: Schmidt’s syndrome also known as autoimmune polyglandular syndrome type 2 (APS type 2) is a rare endocrine disorder defined by the combined occurrence of Addison disease with autoimmune thyroid disease. The rarity of the condition and the atypical presentation of adrenal insufficiency and hypothyroidism often lead to misdiagnosis with life-threatening consequences for the patient. In this study we report an exhaustive monocentric analysis of 22 patients diag...

Introduction: Biermer’s disease is a chronic inflammatory disease due to antibodies targeting parietal cells and intrinsic factor compromising vitamin B12 absorption leading to pernicious anemia, and gastric acid secretion leading to achlorhydria. Neuroendocrine tumors are rare neoplasms that have been reported during the evolution of chronic gastritis. We here describe a case of a type 1 gastric neuroendocrine tumor discovered alongside with Biermer’s disease.<p...

Introduction: Grave’s disease is an autoimmune disorder and is considered the most common cause of hyperthyroidism. Its treatment options include medical therapy, radioactive iodine (RAI), and surgery. RAI is commonly employed for Grave’s disease regarding its efficiency and safety. Definitive hypothyroidism is the main goal of RAI and is typically achieved within the first 3 to 6 months of therapy. Transient hypothyroidism and recurrence of hyperthyroidism after RAI...

Introduction: Pituitary insufficiency is a late-onset sequel of cranial irradiation for nasopharyngeal tumors. In a Cancer Survivor Study, 43% of patients treated for nasopharyngeal tumors had one or more endocrinopathies. We aim to characterize the pituitary-related outcomes following cranial radiotherapy for nasopharyngeal tumors over a period of 5 years.Material and methods: The effects of cranial irradiation on hypothalamic-pituitary function were st...

Introduction: Schmidt’s syndrome also known as autoimmune polyglandular syndrome type 2 (APS type 2) is a rare endocrine disorder defined by the combined occurrence of Addison disease with autoimmune thyroid disease. The rarity of the condition and the atypical presentation of adrenal insufficiency and hypothyroidism often lead to misdiagnosis with life-threatening consequences for the patient. In this study we report an exhaustive monocentric analysis of 22 patients diag...

Context: GH deficiencies could be associated with other pituitary insufficiencies. Our main objective is to assess othe pituitary secretion in short stature patients.Patients and methods: Twenty three patients (17 boys, 6 girls) were included in the study for exploration of short stature, after oral and informed consent of their parents, from January 2016 to June 2017 in the Department of Endocrinology of the University Hospital of Farhat Hached Sousse. ...

Introduction: Congenital adrenal hyperplasia encompasses a spectrum of autosomal recessive disorders marked by enzymatic deficiencies in cortisol biosynthesis. The prevailing etiology predominantly involves a deficit in 21-hydroxylase. This pathophysiological state gives rise to a myriad of complications, with acute adrenal insufficiency standing out as the most critical. Nevertheless, it is noteworthy that less-explored are the intricacies of additional complications, particu...

Introduction: Necrotizing otitis externa (NOE) is a rare but serious condition which is mainly seen in diabetics. This condition has a poor prognosis, due to the complexity of the terrain in which it occurs. The aim of our work is to study the clinical, paraclinical and therapeutic data of NOE. Material and methods: This is a retrospective study covering 64 cases followed and treated in our ENT department over a period of 12 years between 2000 and 2022.<...